朱菲菲，副研究员，feifzhu@ujs.edu.cn
教育经历
2009/08-2014/12，印第安纳大学（美国），分析化学博士，导师：David E. Clemmer
2005/09-2009/06，南京大学，化学化工学院，学士
科研与学术工作经历
2015/11-2016/08，江苏大学生命科学研究院，资格副教授
2019/11-2020/11, 美国明尼苏达大学化学系，访问学者
2016/09-至今，江苏大学生命科学研究院，副研究员
科研方向
昆虫糖生物学和糖基化功能；家蚕抗BmNPV机制；藻类多糖（合作）
主持或参与科研项目：
1. 江苏省自然科学基金青年项目，BK20160509，家蚕蛋白质糖基化在抗质型多角体毒（ BmCPV ）入侵过程中的机制研究， 2016.07 -2019.06 ，20 万，已结题，主持
2. 国家自然科学基金青年项目，31702186，家蚕蛋白质糖基化在BmNPV入侵过程中的分子作用机制，2018.01-2020.12，25万，已结题，主持
3. 国家自然科学基金国际(地区)合作与交流项目，31861143051，家蚕重大病毒病（BmNPV）抗性基因鉴定及抗病毒分子育种，2019-01-01至2021-12-31，170万元，已结题，参与
4. 江苏省自然科学基金面上项目，BK20211320，家蚕脂质糖基化在BmNPV感染机制中的作用研究，2021.07-2024.06, 10万，已结题，主持
5. 国家自然科学基金面上项目，32370387，电活性藻结皮胞外聚合物及其在矿山原位修复中的微电场效应与机制，2024-01-01至2027-12-31，50万元，在研，参与
6.科技部高端外国专家引进计划，G2023014078L，家蚕糖基化图谱的构建，2023.01-2024.12, 26万，已结题，主持
代表论著（一作或通讯）
1.Zhu, F.; Lee, S.; Valentine, S.; Reilly, J.; Clemmer, D. E., Mannose7 Glycan Isomer Characterization by IMS-MS/MS Analysis. J. Am. Soc. Mass Spectrom. 2012, 23, 2158–2166
2.Zhu, F.; Glover, M. S.; Shi, H.; Trinidad, J. C.; Clemmer, D. E., Populations of Metal-Glycan Structures Influence MS Fragmentation Patterns. J. Am. Soc. Mass Spectrom. 2015, 26, 25-35
3.Zhu, F.; Trinidad, C. T.; Clemmer, D. E., Glycopeptide Site Heterogeneity and Structural Diversity Determined by Combined Lectin Affinity Chromatography/IMS/CID/MS Techniques. J. Am. Soc. Mass Spectrom. 2015, 26, 1092-1102.
4.Chen, X.#; Zhu, F.#; Lü, P.; Ma, S.; Nouara, A.; Yang, Y.; Chen, K. Properties of the Bomybx mori insulin-like peptide (BmILP) gene. Invertebrate Surviv. J. 2016,13, 76-88.
5. Zhu, F.; Clemmer, D. E.; Trinidad, J. C. Characterization of Lectin Binding Affinities via Direct LC-MS Profiling: Implications for Glycopeptide Enrichment and Separation Strategies. Analyst, 2016, 142, 65-74.
6.Zhu, F.; Li, D.; Chen, K. P., Structures and functions of invertebrate glycosylation. Open Biology 2019, 9,180232.
7. Zhu, F.; Li, D.; Song, D. D.; Xia, H. C.; Liu, X. Y.; Yao, Q.; Chen, K. P., Precision mapping of n- and o-glycoproteins in viral resistant and susceptible strains of bombyx mori. J. Invertebr. Pathol. 2019, 167, 107250.
8. Li, D.; Chen, X., Zhu, F.*; Chen, K. P*. Insulin like peptides in insects. Invertebrate Survival Journal, 2020, 17, 186-195.
9. Zhu, F.; Li, D.; Song, D.; Huo, S.; Ma, S.; Lü, P.; Liu, X.; Yao, Q.; Chen, K., Glycoproteome in silkworm Bombyx mori and alteration by BmCPV infection. J. Proteomics. 2020, 222, 103802.
10. Zhu, F.; Song, D.; Chen, H.; Tang, Q.; Huo, S.; Liu, X.; Chen, K., A Lipidome Map of the Silkworm Bombyx mori: Influences of Viral Infection. J. Proteome Res. 2021, 20 (1), 695-703.
11. Zhou, W.; Song, D.; Chen, H.; Tang, Q.; Yu, Q.; Huo, S.; Liu, X.; Chen, K.; Zhu, F., Identification of key metabolic pathways reprogrammed by BmNPV in silkworm Bombyx mori. J. Invertebr. Pathol. 2022, 107736.
12. Zhu, F.; Chen, H.; Han, J.; Zhou, W.; Tang, Q.; Yu, Q.; Ma, S.; Liu, X.; Huo, S.; Chen, K., Proteomic and Targeted Metabolomic Studies on a Silkworm Model of Parkinson’s Disease. J. Proteome Res. 2022, 21 (9), 2114-2123.
13. Huo, S.; Wang, H.; Chen, J.; Hu, X.; Zan, X.; Zhang, C.; Qian, J.; Zhu, F.*; Ma, H.; Elshobary, M., A preliminary study on polysaccharide extraction, purification, and antioxidant properties of sugar-rich filamentous microalgae Tribonema minus. Journal of Applied Phycology 2022, 34 (6), 2755-2767.
14. Zhou, W.; Hong, J.; Han, J.; Cai, F.; Tang, Q.; Yu, Q.; Li, G.; Ma, S.; Liu, X.; Huo, S.; Chen, K.; Zhu, F., Silkworm glycosaminoglycans bind to Bombyx mori nuclear polyhedrosis virus and facilitate its entry. Int. J. Biol. Macromol. 2023, 253, 127352.
15. Sobhi, M.; Zakaria, E.; Zhu, F.*; Liu, W.; Aboagye, D.; Hu, X.; Cui, Y.; Huo, S.*, Advanced microbial protein technologies are promising for supporting global food-feed supply chains with positive environmental impacts. Sci. Total Environ. 2023, 894, 165044.
16. Zhu, F.; Han, J.; Hong, J.; Cai, F.; Tang, Q.; Yu, Q.; Ma, S.; Liu, X.; Huo, S.; Chen, K., Characterization of the UDP-glycosyltransferase UGT33D1 in silkworm Bombyx mori. Insect Mol. Biol. 2024, 33 (6), 697-707..
17. Zhu, F.; Hong, J.; Xue, T.; Tang, Q.; Yu, Q.; Li, G.; Ma, S.; Liu, X.; Huo, S.; Chen, K., Bombyx mori nuclear polyhedrosis virus infection regulated by host glycosphingolipids. Pestic. Biochem. Physiol. 2025, 210, 106388.
18. Zhu, F.; Xue, T.; Chen, K., Glycosylation in invertebrate immunity: Host response and pathogen evasion strategies. J. Invertebr. Pathol. 2026, 214, 108503.
更新于2026年9月
